Skip to main content
IKDS 2024 Main banner
Icon Legend
Back

Clinical Management

Poster Hall - Day 2

203 - CHANGING EPIDEMIOLOGY OF KAWASAKI DISEASE: DATA  FROM EASTERN INDIA

Tuesday, August 27, 2024
4:10 PM – 4:30 PM East Coast USA Time
Location: St-Laurent



Introduction:

Over the years it has been noted that there has been a rise in the number of patients diagnosed with Kawasaki disease (KD) with increasing number of patients with CA. Hence, keeping this mind we did this study to assess the epidemiological profile of patients diagnosed as KD from 2009 to August 2023.

METHODOLOGY:

This is a retrospective, analysis of data of patients with KD admitted at Institute of Child Health, Kolkata. Data was compared between pre Covid years with that of post Covid times.



Results:

2009 to Feb 2022: A total of 229 patients were diagnosed as Kawasaki disease this period. 80% were complete KD.  63 (27%) were less than one year of age, 13 were more than 5 years of age (2%), 21 (9%)  had  intravenous immunoglobulin (IVIG) resistant of whom 14 received infliximab (IFX) after IVIG. Over the years the incidence of coronary artery aneurysms (CAA) increased from 15% till 2017 to 17% in 2018 and 32% in 2019 to February 2020. 10 patients had giant coronary artery aneurysms. two of whom with late presentation and intraluminal thrombus of whom one succumbed.

March 2020 to March 2022: This period was majorly affected by COVID 19. A total of 54 patients were diagnosed as Kawasaki disease this period. 16 (30%) were less than one year of age, 3 (6%) were more than 5 years of age, 27 were males, 10 were incomplete KD (19%) , 4  (7%) had  intravenous immunoglobulin (IVIG) resistant who received infliximab (IFX) after IVIG.   15 (28%) had CAA  none giant.

April 2022 to August 2023: 53 patients were diagnosed as KD , 20 (37%) were less than one year of age, 1 (2%) was more than 5 years of age, 63 were males, 21 were incomplete KD (39%) , 6  (11%) had  intravenous immunoglobulin (IVIG) resistant who received infliximab (IFX) after IVIG. 23 (43%) had CAA, none giant. One had intraluminal thrombus formation.

 CONCLUSION

There is an annual rise in the number of patients diagnosed as KD with increasing number of patients with incomplete presentations of KD , rising number of infants rising number of patients with CAA and IVIG resistance.